Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.4
USERS' SCORE
Moderately Good
Based on 66 Reviews
7.8
Supplement Facts
Serving Size: 2 Vegetarian Capsules
Amount Per Serving
%DV
Thiamine (vitamin B1) (as thiamine HCl)
100 mg
8333%
Riboflavin (vitamin B2) (as riboflavin and riboflavin 5'-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
100 mg•
625%
Vitamin B6 (as pyridoxine HCl and pyridoxal 5' phosphate)
100 mg
5882%
Folate (as L-5-methyltetrahydrofolate calcium salt)
680 mcg○
170%
Vitamin B12 (as methylcobalamin)
300 mcg
12500%
Biotin
1000 mcg
3333%
Pantothenic acid (as D-calcium pantothenate)
500 mg
10000%
Calcium (as D-calcium pantothenate, dicalcium phosphate)
50 mg
4%
Inositol
100 mg
**
PABA (para-aminobenzoic acid)
50 mg
**

Top Medical Research Studies

9.5
Vitamin B1 shows promising results
We assessed how effective oral vitamin B1 could be in treating primary dysmenorrhea, which causes significant pelvic pain in young women. In a robust study involving 556 participants aged 12-21 years, we administered 100 mg of vitamin B1 daily for 90 days.

The results were promising, with 87% of participants reportedly completely cured, while 8% experienced some relief. Notably, these positive outcomes persisted for two months after treatment ended, showcasing vitamin B1 as a safe and cost-effective approach to address the root cause of pelvic pain.
Read More
We analyzed various treatments for heavy menstrual bleeding and pain linked to intrauterine device (IUD) use, focusing on randomized controlled trials.

Among the 21 trials we reviewed, we found that vitamin B1 helped reduce bleeding days for Cu IUD users. However, most evidence was weak and uncertain, especially regarding other treatments like naproxen and tranexamic acid, which didn’t show clear benefits.

Overall, more robust studies are essential to confirm these findings and explore vitamin B's role further.
Read More
We looked into how a combination of mannitol and B vitamins could help manage pelvic pain caused by piriformis syndrome. In our study, 22 patients received a five-day intravenous infusion of mannitol and a six-week course of B vitamins.

After treatment, significant improvements were noted in tenderness and pain levels, assessed by various clinical tests and scales. Patients reported less discomfort during rest, activities, and long sitting. Overall, the results suggest that this approach could be an effective alternative for managing piriformis syndrome.
Read More

Most Useful Reviews

7.5
Pain relief noted
279 people found this helpful
Reception of the complex began with a typical mistake: I failed to eat properly. After 20 minutes, I experienced a reaction to niacin: cramping stomach pain, flushing of the face, and redness of the skin on my face, neck, and hands. Fortunately, I am familiar with niacin's effects and did not panic. After drinking two glasses of water, the reaction subsided in 20 minutes. I was impressed by the drug's therapeutic effect. From the first day of taking it, I felt a surge of strength, and the spinal pain decreased. I have been taking it for two weeks now; my lips no longer feel dry, symptoms of post-COVID syndrome have diminished, my training is easier, and my sleep has improved.
Read More
9
Improved health overall
90 people found this helpful
As a man in my 30s, I use this vitamin to enhance my overall health, mood, and well-being. After a month, I noticed an improvement in my overall body health, with no more joint pain. I feel more alert and focused, with enhanced cognitive function and energy levels.
Read More
10
Eliminated pain symptoms
53 people found this helpful
Great vitamins! I have serious spine issues, including protrusions and disc herniation. After trying various vitamins over the years with no effect, I found this complex, which has alleviated my pain syndrome completely, eliminating seasonal exacerbations.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.4
  • All Researches
9.5
Vitamin B1 shows promising results
We assessed how effective oral vitamin B1 could be in treating primary dysmenorrhea, which causes significant pelvic pain in young women. In a robust study involving 556 participants aged 12-21 years, we administered 100 mg of vitamin B1 daily for 90 days.

The results were promising, with 87% of participants reportedly completely cured, while 8% experienced some relief. Notably, these positive outcomes persisted for two months after treatment ended, showcasing vitamin B1 as a safe and cost-effective approach to address the root cause of pelvic pain.
Read More
We looked into how a combination of mannitol and B vitamins could help manage pelvic pain caused by piriformis syndrome. In our study, 22 patients received a five-day intravenous infusion of mannitol and a six-week course of B vitamins.

After treatment, significant improvements were noted in tenderness and pain levels, assessed by various clinical tests and scales. Patients reported less discomfort during rest, activities, and long sitting. Overall, the results suggest that this approach could be an effective alternative for managing piriformis syndrome.
Read More
8
Vitamin B1 showed promise for dysmenorrhea
We explored the effects of vitamin B1 and fish oil on dysmenorrhea in high school students. Conducting a double-blind clinical trial, we observed 240 female students divided into four groups, receiving vitamin B1, fish oil, both, or a placebo over two months.

The results showed that vitamin B1 and fish oil were similarly effective, but vitamin B1 had fewer complications and was better tolerated. Notably, the combination of vitamin B1 and fish oil provided the greatest relief from pain duration compared to the other groups.
Read More
We analyzed various treatments for heavy menstrual bleeding and pain linked to intrauterine device (IUD) use, focusing on randomized controlled trials.

Among the 21 trials we reviewed, we found that vitamin B1 helped reduce bleeding days for Cu IUD users. However, most evidence was weak and uncertain, especially regarding other treatments like naproxen and tranexamic acid, which didn’t show clear benefits.

Overall, more robust studies are essential to confirm these findings and explore vitamin B's role further.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 66 Reviews
7.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Pain relief noted
279 people found this helpful
Reception of the complex began with a typical mistake: I failed to eat properly. After 20 minutes, I experienced a reaction to niacin: cramping stomach pain, flushing of the face, and redness of the skin on my face, neck, and hands. Fortunately, I am familiar with niacin's effects and did not panic. After drinking two glasses of water, the reaction subsided in 20 minutes. I was impressed by the drug's therapeutic effect. From the first day of taking it, I felt a surge of strength, and the spinal pain decreased. I have been taking it for two weeks now; my lips no longer feel dry, symptoms of post-COVID syndrome have diminished, my training is easier, and my sleep has improved.
Read More
9
Improved health overall
90 people found this helpful
As a man in my 30s, I use this vitamin to enhance my overall health, mood, and well-being. After a month, I noticed an improvement in my overall body health, with no more joint pain. I feel more alert and focused, with enhanced cognitive function and energy levels.
Read More
10
Eliminated pain symptoms
53 people found this helpful
Great vitamins! I have serious spine issues, including protrusions and disc herniation. After trying various vitamins over the years with no effect, I found this complex, which has alleviated my pain syndrome completely, eliminating seasonal exacerbations.
Read More
8
Mood enhancement observed
39 people found this helpful
This is excellent and effectively works! I combined it with Alkar and SAM'e. Without vitamin B, my stomach ached, but once I started taking it, that pain disappeared. My urine did turn bright yellow after the first dose, which is normal, as the excess is expelled. I felt the effects of the vitamins immediately; my mood improved, my hair became shinier, and I find it easier to gain muscle mass and withstand heavy loads. I highly recommend it for both athletes and regular use.
Read More
7.5
Anxiety alleviated
37 people found this helpful
Wonderful! The effects are strong and potent. I took it to praise a friend after explaining my symptoms, and it's excellent for fatigue. It boosts physical activity greatly, so I take it after breakfast each day. My mood has improved significantly. I suffer from anxiety, tension, and difficulty in focusing, and I’ve endured pain in my upper back, shoulders, neck, and joints for years. Remarkably, that pain has eased considerably, and I highly recommend it.
Read More

Frequently Asked Questions

9
Back pain relief
1 people found this helpful
Great choice! An excellent complex of B vitamins, easily digestible; my pelvic pain has disappeared.
9
Effective for facial nerve
1 people found this helpful
In the initial days, I took two capsules but later switched to one, as the daily dosage in one pill is quite high. After two weeks, the pain from my inflamed facial nerve disappeared. Although the capsules have an unpleasant odour, the complex seems effective.
9
Relieved sciatic pain
1 people found this helpful
Thanks to Life Extension B complex! It helped with my sciatic pain. After three days of discomfort, I took it immediately when it arrived. Following the two capsules per day, I noticed significant improvement. The quality and ingredients are excellent with no aftertaste. I will reorder again. Highly recommended!
10
Resolved pain issues
31 people found this helpful
A good complex of B vitamins with active forms for better absorption. I ordered this for myself and my mother, as she often complained of muscle pain and finger numbness. The results are good; her pain and numbness have reduced even before finishing the complex. I highly recommend it.
10
Eliminated pain symptoms
53 people found this helpful
Great vitamins! I have serious spine issues, including protrusions and disc herniation. After trying various vitamins over the years with no effect, I found this complex, which has alleviated my pain syndrome completely, eliminating seasonal exacerbations.
9
90% pain relief
5 people found this helpful
Very good! I suffered from sciatica, back pain, and coccyx pain, all of which reduced by 90%. Thankfully, I do not recommend daily use, as it is a very strong supplement.
7.5
Anxiety alleviated
37 people found this helpful
Wonderful! The effects are strong and potent. I took it to praise a friend after explaining my symptoms, and it's excellent for fatigue. It boosts physical activity greatly, so I take it after breakfast each day. My mood has improved significantly. I suffer from anxiety, tension, and difficulty in focusing, and I’ve endured pain in my upper back, shoulders, neck, and joints for years. Remarkably, that pain has eased considerably, and I highly recommend it.
9
Pain mechanisms resolved
1 people found this helpful
I bought this for its affordability and composition. The capsules are quite large, but I can swallow them one by one without trouble. Working at a desk, I previously suffered from intense pain in the evenings that made it hard to keep my eyes open. Taking two tablets each morning has nearly eliminated that pain for me, and if I take one when the pain strikes, it vanishes instantly. This product has been a tremendous help in my daily life.
8
Mood enhancement observed
39 people found this helpful
This is excellent and effectively works! I combined it with Alkar and SAM'e. Without vitamin B, my stomach ached, but once I started taking it, that pain disappeared. My urine did turn bright yellow after the first dose, which is normal, as the excess is expelled. I felt the effects of the vitamins immediately; my mood improved, my hair became shinier, and I find it easier to gain muscle mass and withstand heavy loads. I highly recommend it for both athletes and regular use.
9
Back pain relief
5 people found this helpful
For years, I suffered from back pain due to protrusions and hernias. Various treatments like massage and acupuncture offered only temporary relief. While taking B vitamins to reduce homocysteine, I was surprised to find that my back pain subsided for six months. I had remaining vitamins and completed the regimen. It has now been a year without pain, which is remarkable!
9.5
Vitamin B1 shows promising results
We assessed how effective oral vitamin B1 could be in treating primary dysmenorrhea, which causes significant pelvic pain in young women. In a robust study involving 556 participants aged 12-21 years, we administered 100 mg of vitamin B1 daily for 90 days.

The results were promising, with 87% of participants reportedly completely cured, while 8% experienced some relief. Notably, these positive outcomes persisted for two months after treatment ended, showcasing vitamin B1 as a safe and cost-effective approach to address the root cause of pelvic pain.
We looked into how a combination of mannitol and B vitamins could help manage pelvic pain caused by piriformis syndrome. In our study, 22 patients received a five-day intravenous infusion of mannitol and a six-week course of B vitamins.

After treatment, significant improvements were noted in tenderness and pain levels, assessed by various clinical tests and scales. Patients reported less discomfort during rest, activities, and long sitting. Overall, the results suggest that this approach could be an effective alternative for managing piriformis syndrome.
8
Vitamin B1 showed promise for dysmenorrhea
We explored the effects of vitamin B1 and fish oil on dysmenorrhea in high school students. Conducting a double-blind clinical trial, we observed 240 female students divided into four groups, receiving vitamin B1, fish oil, both, or a placebo over two months.

The results showed that vitamin B1 and fish oil were similarly effective, but vitamin B1 had fewer complications and was better tolerated. Notably, the combination of vitamin B1 and fish oil provided the greatest relief from pain duration compared to the other groups.
We analyzed various treatments for heavy menstrual bleeding and pain linked to intrauterine device (IUD) use, focusing on randomized controlled trials.

Among the 21 trials we reviewed, we found that vitamin B1 helped reduce bleeding days for Cu IUD users. However, most evidence was weak and uncertain, especially regarding other treatments like naproxen and tranexamic acid, which didn’t show clear benefits.

Overall, more robust studies are essential to confirm these findings and explore vitamin B's role further.

References

  1. Christelle K, Norhayati MN, Jaafar SH. Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine-device use. Cochrane Database Syst Rev. 2022;8:CD006034. 10.1002/14651858.CD006034.pub3
  2. Huang ZF, Lin BQ, Torsha TT, Dilshad S, Yang DS, et al. Effect of Mannitol plus Vitamins B in the management of patients with piriformis syndrome. J Back Musculoskelet Rehabil. 2019;32:329. 10.3233/BMR-170983
  3. Hosseinlou A, Alinejad V, Alinejad M, Aghakhani N. The effects of fish oil capsules and vitamin B1 tablets on duration and severity of dysmenorrhea in students of high school in Urmia-Iran. Glob J Health Sci. 2014;6:124. 10.5539/gjhs.v6n7p124
  4. Gokhale LB. Curative treatment of primary (spasmodic) dysmenorrhoea. Indian J Med Res. 1996;103:227.
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